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Buchler GmbH
D-38110 Braunschweig
Harxb
Ütteler Strasse 3
Tel.  ++ 49  5307  93121
eMail:
himstedt@buchler-gmbh.com
and   
 wedde@buchler-gmbh.com

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Quinic acid

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Quinic acid as a sugar compound from nature is found in many different
plants, such  as tobacco leaves,  carrot  leaves,  apples,  peaches,  pears,
plums,  vegetables  etc. 
Quinic acid and of course Shikimic acid
are key
intermediates in the biosynthesis of aromatic compounds in living systems.

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TAMIFLU

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Quinic acid is a versatile chiral starting material for the synthesis of new
pharmaceuticals. A new medicament for the treatment of influenza
A- and B-strains called Tamiflu has been successfully
developed and launched into the market recently.

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.i

influenza neuraminidase inhibitor
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The active ingredient GS 4104 inhibits a key enzyme needed for
replication of the flu virus in host cells (J. Am. Chem. Soc. 1997, 119, 681)

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