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| Quinic acid |
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Quinic acid as a sugar compound from nature is found in many different
plants, such as tobacco leaves, carrot leaves, apples, peaches, pears,
plums, vegetables etc. Quinic acid and of course Shikimic acid are key
intermediates in the biosynthesis of aromatic compounds in living systems. |
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| TAMIFLU |
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Quinic acid is a versatile chiral
starting material for the synthesis of new
pharmaceuticals. A new medicament for the
treatment of influenza
A- and B-strains called Tamiflu has been
successfully
developed and launched into the market recently. |
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 |
.i
influenza
neuraminidase inhibitor
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The active ingredient GS 4104 inhibits a key enzyme needed for
replication of
the flu virus in host cells (J. Am. Chem. Soc. 1997, 119, 681). |
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